Csf2ra
Webcolony stimulating factor 2 receptor alpha subunit : Nomenclature updated to reflect human and mouse nomenclature: 1299863: APPROVED: 2016-01-20: Csf2ra : colony … WebDec 3, 2015 · CSF2RA expression also reduced the stemness of RUNX1-ETO bone marrow cells and inhibited their colony forming ability. To identify which region of the receptor was mediating these pro-apoptotic effects, we generated truncation mutants and determined that the 25 amino acids at the carboxyl-terminus of the intracellular domain of CSF2RA are …
Csf2ra
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WebDescription: Homo sapiens colony stimulating factor 2 receptor subunit alpha (CSF2RA), transcript variant 7, mRNA. (from RefSeq NM_001161529) RefSeq Summary (NM_001161529): The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the … WebDec 10, 2024 · Csf2ra is a receptor for GM-CSF, a growth factor that promotes survival and activation of several immune cells including macrophages , and is important in mediating tissue inflammation . …
WebThe protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a c ytokine which controls the production, differentiation, and … WebOrder. Sequence variants and/or copy number variants (deletions/duplications) within the CSF2RA gene will be detected with >99% sensitivity. Variants classified as unknown …
WebApr 8, 2024 · Harnessing the potential of this approach for gene therapy, we restored a disrupted Csf2ra gene in fetal liver monocytes and demonstrated their capacity to develop into alveolar macrophages in vivo. Altogether, we provide a platform for generation of immature alveolar macrophage-like precursors amenable for genetic manipulation, which … WebBy using this site, you agree to our Terms and Conditions Got it!
WebSep 20, 2024 · To test this, colony stimulating factor 2 receptor alpha (Csf2ra) knockout (KO) mice that lack GM-CSF signaling and wild-type (WT) mice models of intratracheal …
WebApr 13, 2024 · 构建重组asfv- cd2v缺失毒株可下调jak2-stat3信号通路,诱导细胞凋亡。酵母双杂交系统筛选发现病毒蛋白cd2v与宿主蛋白csf2ra互作(图c),csf2ra是存在于髓系细胞中造血受体超家族成员,具有上调jak2和stat3蛋白表达水平的功能。 bucs quarterbacks 2020WebGenetic Factors. A series of reports have now established hereditary PAP as a newly described genetic disease caused by genetic mutations in CSF2RA or CSF2RB, which encode GM-CSF receptor α or β chains, respectively ( Fig. 70-3 ). 23-25,52,53 In some cases, the genes have been cloned, the defects reproduced in vitro, the signaling ... bucs quarterbacks 2021WebCSF2RA colony stimulating factor 2 receptor subunit alpha [ (human)] Gene ID: 1438, updated on 26-Oct-2024. Summary. The protein encoded by this gene is the alpha … bucs radio stationsWebDec 3, 2015 · CSF2RA expression also reduced the stemness of RUNX1-ETO bone marrow cells and inhibited their colony forming ability. To identify which region of the receptor … bucs qb 2018WebHuman Gene CSF2RA (uc004cpp.2) Description: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 3, mRNA. RefSeq Summary (NM_172246): cress go boletoWebDescription: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 11, non-coding RNA. RefSeq Summary (NR_027760): bucs quarterbacksCSF2RA (Colony Stimulating Factor 2 Receptor Subunit Alpha) is a Protein Coding gene. Diseases associated with CSF2RA include Surfactant Metabolism Dysfunction, Pulmonary, 4 and Hereditary Pulmonary Alveolar Proteinosis.Among its related pathways are RAF/MAP kinase cascade and Interleukin-2 family signaling.Gene Ontology (GO) annotations related to this gene include signaling receptor activity ... cress gmbh