Phenolic phthiocerol
WebDistribution of Phthiocerol Diester, Phenolic Mycosides and Related Compounds in Mycobacteria Microbiology Society Volume 134, Issue 7 Research Article Free … WebApr 30, 2014 · Peripheral blood monocytes were pretreated with phenolic glycolipid-I (PGL-I), dimycocerosyl phthiocerol (DIM), or mycoside A, then cultured in the presence or absence of interferon-gamma (IFN-gamma).
Phenolic phthiocerol
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WebPhenolic phthiocerol C37H68O4 CID 45266796 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … WebOct 1, 2014 · TLDR This review will focus on phthiocerol dimycocerosates (PDIMs), a long-known and well-studied group of complex lipids found in the M. tuberculosis cell envelope that have an involvement in bacterial virulence, in association with the ESX-1 secretion system. 9 Mycobacterium tuberculosis metabolism. D. Warner Biology, Medicine
WebChEBI Name phenolic glycolipid-1: ChEBI ID CHEBI:59104: Definition A lipooligosaccharide whose structure comprises a phenolic phthiocerol core linked to a unique trisaccharide (3,6-di-O-methyl-α-D-glucopyranosyl-(1→4)-2,3-di-O-methyl-α-L-rhamnopyranosyl-(1→2)-3-O-methyl-α-L-rhamnopyranose) at one end and a mixture of long-chain mycocerosyl fatty … WebNov 16, 2015 · The phthiocerol family consists of phthiocerol A, phthiocerol B, phthiodiolone A, and phthiotriol A, of which phthiocerol A and phthiodiolone A are the most commonly present. In M. marinum , a major analogous PGL family consisting of the long-chain β-diol backbone modified with a phenolic group at the terminal, to which a 3- O …
Webphenolic: (fĭ-nō′lĭk, -nŏl′ĭk) adj. Of, relating to, containing, or derived from phenol. n. Any of various synthetic thermosetting resins, obtained by the reaction of phenols with simple … WebOct 11, 1983 · Mycocerosic acids are diesterified to the phthiocerols, with the resultant phthiocerol dimycocerosate being over 100 carbons in size and highly resistant to hydrolysis.45 Additionally, mycocerosic acids are present as the lipid moiety in phenolic glycolipids (PGLs) found in M. bovis and unusual “Canetti” variants of M. …
WebJan 26, 2016 · Phthiocerol dimycocerosates (PDIMs) and phenolic glycolipids (PGLs) contribute to the pathogenicity of several mycobacteria. Biosynthesis of these virulence factors requires polyketide synthases and other enzymes that represent potential targets for the development of adjuvant antivirulence drugs.
WebPhenolic compounds are classified as simple phenols or polyphenols based on the number of phenol units in the molecule. Phenol – the simplest of the phenols Chemical structure … clickshare c10 anleitungWebJun 26, 2024 · It consists of a lipid phthiocerol dimycoserosate and a phenolic glycolipid. This glycolipid is made up of three methylated sugars linked by phenol to phthiocerol (fat), known as phenolic glycolipid or PGL; it is chemically unique and the trisaccharide is referred to as specific to M. leprae. clickshare c3010s setupWebPhthiocerol dimycocerosates (PDIMs) and structurally related phenolic glycolipids (PGLs) are complex cell wall lipids unique to pathogenic mycobacteria. While these lipids have … clickshare c5010s firmwareWebAcid hydrolysis of deacylated Phenolic glycolipid-I yielded a phenolic phthiocerol "core," and mass spectrometry and proton NMR of the permethylated core suggested the following structure: (formula, see text) Combined gas-liquid chromatography-mass spectrometry showed three tetramethyl branched "mycocerosic" acids, C30, C32 and C34, with … bnf buccastemWebAccording, a diacylphenolicphthiocerol was ruled out. The putative diacylphthiocerol (24 mg) was dissolved in 500 pl of benzene and refluxed with 1 ml of 15% KOH in methanol. … bnf buccastem mWebspecies-specific segment of a phenolic phthiocerol-containing glycolipid (phenolic glycolipid I) that is found in large quantities in the leprosy bacillus and in lepromatous leprosy (LL) tissue [1, 2] and is highly specific for the serodiagnosis of leprosy [3-5]. We have recently described the synthesis and clickshare c10 setupWebDec 9, 2014 · Here, we will address exclusively the proposed role for phthiocerol dimycocerosates (DIM) in the modulation of the resident macrophage response and that of phenolic glycolipids (PGL) in the regulation of the recruitment and phenotype of incoming macrophage precursors to the site of infection. clickshare c3010s firmware